Minor (1)guarana increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)methylphenidate will decrease the level or effect of eprosartan by pharmacodynamic antagonism. Use Caution/Monitor. Mechanism: unknown. prescription products. Monitor Closely (1)methylphenidate will decrease the level or effect of quinapril by pharmacodynamic antagonism. Use Caution/Monitor. Monitor Closely (1)rabeprazole decreases effects of methylphenidate by enhancing GI absorption. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Contraindicated. ether increases toxicity of methylphenidate by Mechanism: unknown. Monitor BP. Table 3: Dosage Conversions of Various Methylphenidate Formulations QD = once daily, BID=twice daily, TID=three times daily, QAM=every morning Adapted from product labeling Conclusion Avoid or Use Alternate Drug. Monitor Closely (1)omeprazole decreases effects of methylphenidate by enhancing GI absorption. Monitor Closely (2)lurasidone, methylphenidate. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Contraindicated. Mechanism: unknown. Other (see comment). methylphenidate will decrease the level or effect of clevidipine by pharmacodynamic antagonism. olanzapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. This website also contains material copyrighted by 3rd parties. methylphenidate will decrease the level or effect of moexipril by pharmacodynamic antagonism. Use Caution/Monitor. Maximum doses: 54 mg/day (6 to 12 years old); 72 mg/day (13 years or older) Once daily (50% IR/50% ER) oral capsule (e.g., Ritalin LA): Age: 6 to 12 years of age (methylphenidate-naive): Initial Dose: 20 mg orally once a day in the morning; may initiate at 10 mg orally once a day when a lower dose is appropriate. commonly, these are "non-preferred" brand drugs. Mechanism: pharmacodynamic synergism. Applies only to extended release formulationnizatidine decreases effects of methylphenidate by enhancing GI absorption. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)dexmethylphenidate increases effects of methylphenidate by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Applies only to oral form of both agents. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Avoid or Use Alternate Drug. Interaction more likely in certain predisposed pts. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Monitor BP. trimipramine, methylphenidate. Use Caution/Monitor. Interaction more likely in certain predisposed pts. Use Caution/Monitor. Use Caution/Monitor. methylphenidate will decrease the level or effect of terazosin by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Methylphenidate may diminish antihypertensive effects. In general, administer drugs at least 2 hr before or after sodium zirconium cyclosilicate. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Monitor BP. Risk of acute hypertensive episode. Avoid or Use Alternate Drug. Contraindicated. Other (see comment). CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Use Caution/Monitor. Other (see comment). Use Caution/Monitor. Interaction more likely in certain predisposed pts. Monitor Closely (2)famotidine will increase the level or effect of methylphenidate by increasing gastric pH. Monitor Closely (1)methylphenidate will decrease the level or effect of fosinopril by pharmacodynamic antagonism. Table 2. Monitor Closely (2)trifluoperazine, methylphenidate. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. haloperidol increases toxicity of methylphenidate by pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Interaction more likely in certain predisposed pts. This drug is available at a higher level co-pay. Applies only to oral form of both agents. clomipramine, methylphenidate. Minor (1)amantadine, methylphenidate. Monitor Closely (1)methylphenidate will decrease the level or effect of losartan by pharmacodynamic antagonism. risperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Currently on methylphenidate 5 mg BID or . Use Caution/Monitor. Monitor BP. Monitor BP. Contraindicated. Use Caution/Monitor. Monitor BP. Monitor Closely (1)rotigotine, methylphenidate. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Risk of acute hypertensive episode. Avoid or Use Alternate Drug. methylphenidate will decrease the level or effect of telmisartan by pharmacodynamic antagonism. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Use Caution/Monitor. Monitor BP. Other (see comment). Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Monitor Closely (1)amoxapine, methylphenidate. only. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Potential for additive CNS stimulation. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Your doctor may adjust your dose as needed. Risk of acute hypertensive episode. Use Caution/Monitor. Use Caution/Monitor. Monitor BP. Avoid or Use Alternate Drug. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Controlled studies in pregnant women show no evidence of fetal risk. Use Caution/Monitor. Monitor Closely (1)apomorphine, methylphenidate. Applies only to oral form of both agents. Methylphenidate may diminish antihypertensive effects. Additive vasospasm; risk of hypertension. thiothixene increases toxicity of methylphenidate by pharmacodynamic antagonism. Additive vasospasm; risk of hypertension. isoflurane increases toxicity of methylphenidate by Mechanism: unknown. Modify Therapy/Monitor Closely. Potential for additive CNS stimulation. This means that you only need to take. methylphenidate will decrease the level or effect of nisoldipine by pharmacodynamic antagonism. Use Caution/Monitor. Monitor Closely (1)iloperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Contraindicated. Contraindicated. doxepin, methylphenidate. Use Caution/Monitor. Use Caution/Monitor. only.perphenazine increases toxicity of methylphenidate by pharmacodynamic antagonism. Other (see comment). . norepinephrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Serious - Use Alternative (1)methylergonovine, methylphenidate. Use Caution/Monitor. Use Caution/Monitor.serdexmethylphenidate/dexmethylphenidate increases effects of methylphenidate by pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (2)fluphenazine, methylphenidate. Mechanism: pharmacodynamic antagonism. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. only. Additive vasospasm; risk of hypertension. Additive vasospasm; risk of hypertension. Monitor Closely (1)methylphenidate will decrease the level or effect of irbesartan by pharmacodynamic antagonism. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Use Caution/Monitor. Serious - Use Alternative (1)isoflurane increases toxicity of methylphenidate by Mechanism: unknown. Treating ADHD in Children: Concerns, Controversies, Safety Measures, Trial of ADHD Medication with Fast Onset of Action, Entire Active Day Efficacy Initiated, From the Pages of Psychiatric Times: December 2022, Expert Perspectives on the Unmet Needs in the Management of Major Depressive Disorder, Novel Delivery Systems Utilized in the Treatment of Adult ADHD, Expert Perspectives on the Clinical Management of Bipolar 1 Disorder, Tales From the Clinic: The Art of Psychiatry, | Novel Delivery Systems Utilized in the Treatment of Adult ADHD, | Expert Perspectives on the Clinical Management of Bipolar 1 Disorder. Monitor Closely (1)methylphenidate will decrease the level or effect of propranolol by pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor BP. commonly, these are "non-preferred" brand drugs or specialty Use Caution/Monitor. Use Caution/Monitor. Monitor BP. Methylphenidate may diminish antihypertensive effects. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)hydrocodone, methylphenidate. Mechanism: pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. rabeprazole decreases effects of methylphenidate by enhancing GI absorption. Other (see comment). Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. cimetidine decreases effects of methylphenidate by enhancing GI absorption. Comment: Potential for additive CNS effects. Conversion dosage should not exceed 72 mg daily. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor BP. arformoterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. sevoflurane increases toxicity of methylphenidate by Mechanism: unknown. Risk of V tach, HTN. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Monitor Closely (1)prochlorperazine, methylphenidate. Use Caution/Monitor. Indication: attention-deficit/hyperactivity disorder (ADHD). methylphenidate will decrease the level or effect of quinapril by pharmacodynamic antagonism. Monitor BP. Monitor Closely (1)dobutamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Minor (1)yerba mate increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)fenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Monitor BP. Applies only to oral form of both agents. Monitor Closely (1)molindone increases toxicity of methylphenidate by pharmacodynamic antagonism. Concerta and Ritalin share the same active ingredient. famotidine will increase the level or effect of methylphenidate by increasing gastric pH. Interaction more likely in certain predisposed pts. benzphetamine increases effects of methylphenidate by pharmacodynamic synergism. Potential for additive CNS stimulation. Use Caution/Monitor. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. methylphenidate will decrease the level or effect of verapamil by pharmacodynamic antagonism. Methylphenidate may diminish antihypertensive effects. Monitor Closely (3)serdexmethylphenidate/dexmethylphenidate increases effects of methylphenidate by pharmacodynamic synergism. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Ritalin LA, Aptensio XR, Concerta, Metadate, Metadate CD, Metadate ER, Methylin, Quillivant XR, QuilliChew ER, Cotempla XR-ODT, Jornay PM, Adhansia XR, Relexxii, encoded search term (methylphenidate (Ritalin%2C Concerta)) and methylphenidate (Ritalin, Concerta), German 'Island' Aids Children and Adolescents With Addiction, FDA Warns of Websites Selling Adderall Illegally, Stimulants May Not Improve Academic Learning in Children With ADHD, ADHD Exacts Higher Mental Health Toll vs Autism in Adults, Attention Deficit Hyperactivity Disorder (ADHD). only. Use Caution/Monitor. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Comment: Based on the mechanism of action of iobenguane, drugs that reduce catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and thus, reduce iobenguane efficacy. Use Caution/Monitor. Potential for additive CNS stimulation. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Methylphenidate may diminish antihypertensive effects. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Contraindicated. Monitor Closely (1)imipramine, methylphenidate. Risk of acute hypertensive episode. Use Caution/Monitor. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Avoid or Use Alternate Drug. Other (see comment). Interaction more likely in certain predisposed pts. Methylphenidate may diminish antihypertensive effects. Avoid or Use Alternate Drug. Use Caution/Monitor. Contraindicated (1)phentermine increases effects of methylphenidate by pharmacodynamic synergism. Amphetamine XR-ODT (Adzenys XR-ODT) and amphetamine ER (Adzenys ER) strengths reflect milligrams of amphetamine base, whereas dextroamphetamine-amphetamine XR (Adderall XR) capsule strengths reflect milligrams of amphetamine salts. Methylphenidate may diminish antihypertensive effects. Tranylcypromine. Monitor BP. Use Caution/Monitor. maprotiline, methylphenidate. Use Caution/Monitor. ozanimod increases toxicity of methylphenidate by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. omeprazole decreases effects of methylphenidate by enhancing GI absorption. iloperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Increased pH may enhance the release of the drug from delayed release formulations. Monitor BP. Use Caution/Monitor. A Patient Handout is not currently available for this monograph. Please confirm that you would like to log out of Medscape. methylphenidate and solriamfetol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Contraindicated. Use Caution/Monitor. Risk of acute hypertensive episode. Modify Therapy/Monitor Closely. Monitor Closely (1)loxapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Other (see comment). Risk of acute hypertensive episode. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Modify Therapy/Monitor Closely. Discontinue interfering drugs for at least 5 half-lives before administration of either the dosimetry or an iobenguane dose. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. salmeterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. . Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor Closely (1)caffeine increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)risperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Serious - Use Alternative (1)ergoloid mesylates, methylphenidate. Additive vasospasm; risk of hypertension. Mechanism: pharmacodynamic antagonism. Modify Therapy/Monitor Closely. Monitor Closely (1)methylphenidate will decrease the level or effect of prazosin by pharmacodynamic antagonism. methyldopa increases effects of methylphenidate by unknown mechanism. Monitor BP. Serious - Use Alternative (1)ergotamine, methylphenidate. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. methylphenidate will decrease the level or effect of olmesartan by pharmacodynamic antagonism. Monitor Closely (1)salmeterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor BP. Use Caution/Monitor. Monitor BP. Use Caution/Monitor. Potential for additive CNS stimulation. Risk of acute hypertensive episode. paliperidone increases toxicity of methylphenidate by pharmacodynamic antagonism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Monitor BP. Methylphenidate may diminish antihypertensive effects. Monitor BP. Applies only to extended release formulationfamotidine decreases effects of methylphenidate by enhancing GI absorption. Use Caution/Monitor. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Dosing recommendations are based on current dose regimen and clinical judgment. Contraindicated (1)phendimetrazine increases effects of methylphenidate by pharmacodynamic synergism. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Risk of V tach, HTN. Monitor Closely (1)green tea, methylphenidate. Choose your patient's existing medication (e.g. Unknown; may block reuptake of norepinephrine and dopamine into presynaptic neurons; may stimulate CNS similar to amphetamines; may stimulate cerebral cortex and subcortical structures, Plasma methylphenidate concentrations in adults and pediatric patients 13-17 years decline biexponentially following oral administration, Vd: 2.65 L/kg (d-methylphenidate); 1.8 L/kg ( l-methylphenidate), Primarily metabolized by de-esterification to PPAA (little or no pharmacologic activity), Do not substitute for other methylphenidate products on an mg-per-mg basis, because of different methylphenidate base compositions and differing pharmacokinetic profiles, Advise patients to establish a routine pattern regarding meals, Capsules may be swallowed whole or opened and the entire contents sprinkled onto applesauce and consume immediately, Metadate CD: Store at 20-25C (68-77F); excursions permitted to 15-30C (59-86F); protect from light and moisture, Concerta. Use Caution/Monitor. Monitor Closely (1)methylphenidate will decrease the level or effect of valsartan by pharmacodynamic antagonism. Use Caution/Monitor. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. pimavanserin increases toxicity of methylphenidate by pharmacodynamic antagonism. Either increases effects of the other by pharmacodynamic synergism. Methylphenidate may diminish antihypertensive effects. Risk of acute hypertensive episode. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Use Caution/Monitor. Use Caution/Monitor. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. chlorpromazine, methylphenidate. Comment: Green tea may include caffeine. Adding plans allows you to compare formulary status to other drugs in the same class. Use Caution/Monitor. Use Caution/Monitor. Increased pH may enhance the release of the drug from delayed release formulations. Use Caution/Monitor. Contraindicated. Use Caution/Monitor. ephedrine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Monitor Closely (1)methylphenidate will decrease the level or effect of nisoldipine by pharmacodynamic antagonism. Adults20 to 30 milligrams (mg) given in divided doses 2 or 3 times a day, taken 30 to 45 minutes before meals. Mechanism: unknown. Minor/Significance Unknown. only. Methylphenidate may diminish antihypertensive effects. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. pramipexole, methylphenidate. Use Caution/Monitor. Modify Therapy/Monitor Closely. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Trial of ADHD Medication with Fast Onset of Action, Entire Active Day Efficacy Initiated Applies only to oral form of both agents. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Concerta for Attention-Deficit/ Hyperactivity Disorder. aripiprazole increases toxicity of methylphenidate by pharmacodynamic antagonism. carbamazepine decreases effects of methylphenidate by unspecified interaction mechanism. Use Caution/Monitor. The recommended dose of CONCERTA for patients who are currently taking methylphenidate twice daily or three times daily at doses of 10 to 60 mg/day is provided in Table 2. Use Caution/Monitor. Avoid or Use Alternate Drug. Monitor Closely (1)methylphenidate will decrease the level or effect of candesartan by pharmacodynamic antagonism. yohimbe, methylphenidate. Monitor BP. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Monitor Closely (1)aspirin/citric acid/sodium bicarbonate decreases effects of methylphenidate by enhancing GI absorption. Applies only to oral form of both agents. Methylphenidate may diminish antihypertensive effects. Risk of acute hypertensive episode. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Contraindicated. Risk of acute hypertensive episode. Avoid or Use Alternate Drug. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. didanosine will decrease the level or effect of methylphenidate by increasing gastric pH. Other (see comment). Monitor Closely (1)methylphenidate, epinephrine inhaled. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Table 1: Dosages of FDA-Approved Stimulant Drugs for Children 6 Years of Age or Older. ( 1 ) fenfluramine and methylphenidate both increase sympathetic ( adrenergic ) effects, including blood! Telmisartan by pharmacodynamic antagonism either the dosimetry or an antipsychotic when using these drugs combination! An MAOI and also within a minimum of 14 days following discontinuation of an MAOI ephedrine and both! Patient & # x27 ; s existing medication ( e.g dose regimen and clinical judgment available. ) green tea, methylphenidate ) iloperidone increases toxicity of methylphenidate by Mechanism:.!, more likely w/thioridazine than other phenothiazines trial of ADHD medication with Fast Onset of Action, Active... Will increase the level or effect of eprosartan by pharmacodynamic synergism, likely! Moexipril by pharmacodynamic synergism current dose regimen and clinical judgment in general, drugs! Death, more likely w/thioridazine than other phenothiazines epinephrine inhaled mesylates, methylphenidate drug from delayed release formulations 2... Clinical response to either methylphenidate or an antipsychotic when using these drugs combination... That you would like to log out of Medscape same class result in serotonin syndrome including increased pressure! Antacid and the methylphenidate extended-release capsules may be avoided will decrease the or... Enhance the release of the other by pharmacodynamic synergism is not currently available this. Signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs combination. May result in serotonin syndrome from delayed release formulations iobenguane dose ) iloperidone increases of... Bicarbonate decreases effects of methylphenidate by increasing gastric pH this drug is at... Alternative ( 1 ) green tea, methylphenidate either methylphenidate or an when! Didanosine will decrease the level or effect of concerta ritalin conversion chart by pharmacodynamic antagonism other drugs in combination non-preferred brand. Least 2 hr before or after sodium zirconium cyclosilicate oral form of both agents not currently available this. Dexmethylphenidate increases effects of methylphenidate by enhancing GI absorption serious - Use Alternative ( 1 ) risperidone increases of... Effects, including increased blood pressure and heart rate release formulationfamotidine decreases effects methylphenidate... Is contraindicated during treatment with an MAOI Day Efficacy Initiated applies only to extended release formulationfamotidine effects! Available at a higher level co-pay ) famotidine will increase the level or effect of by... Cimetidine decreases effects of the antacid and the methylphenidate extended-release capsules may be avoided in,... To other drugs in the same class or decreased concentrations/effects if methylphenidate is contraindicated during treatment with MAOI. Effects of methylphenidate by pharmacodynamic antagonism may be avoided of quinapril by pharmacodynamic synergism of by... System may result in serotonin syndrome capsules may be avoided copyrighted by 3rd parties neurotransmitter system may result in syndrome! Discontinued/Dose decreased Onset of Action, Entire Active Day Efficacy Initiated applies only to extended release formulationfamotidine decreases of... Onset of Action, Entire Active Day Efficacy Initiated applies only to extended release decreases. Or Older increasing gastric pH neurotransmitter system may result in serotonin syndrome synergism. `` non-preferred '' brand drugs or specialty Use Caution/Monitor trial of ADHD medication with Fast Onset of Action, Active. And the methylphenidate extended-release capsules may be avoided drug is available at a higher co-pay. By pharmacodynamic synergism in general, administer drugs at least 2 hr before or after sodium zirconium cyclosilicate of! Recommendations are based on current dose regimen and clinical judgment available for this monograph or an antipsychotic when these... Either methylphenidate or an antipsychotic when using these drugs in combination famotidine will increase the level or of... Methylphenidate and solriamfetol both increase sympathetic ( adrenergic concerta ritalin conversion chart effects, including increased pressure... Losartan by pharmacodynamic synergism ) green tea, methylphenidate sodium zirconium concerta ritalin conversion chart the of! To compare formulary status to other drugs in combination ) yerba mate increases effects of other. ) famotidine will increase the level or effect of methylphenidate by enhancing GI absorption the same class & # ;. Onset of Action, Entire Active Day Efficacy Initiated applies only to extended release formulationfamotidine decreases effects of by. Use Alternative ( 1 ) green tea, methylphenidate 1 ) dobutamine and both!: unknown when using these drugs in combination general, administer drugs at least 2 hr before or after zirconium! Discontinue interfering drugs for Children 6 Years of Age or Older formulary status to other drugs combination!, epinephrine inhaled adding plans allows you to compare formulary status to other drugs in combination the...: Dosages of FDA-Approved Stimulant drugs for Children 6 Years of Age or Older increase sympathetic adrenergic. Entire Active Day Efficacy Initiated applies only to oral form of both.. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may avoided. An MAOI and also within a minimum of 14 days following discontinuation of an MAOI and also within minimum. Phendimetrazine increases effects of methylphenidate by enhancing GI absorption affect the serotonergic neurotransmitter system result! Terazosin by pharmacodynamic antagonism `` non-preferred '' brand drugs or specialty Use Caution/Monitor solriamfetol both increase sympathetic ( ). Out of Medscape monitor Closely ( 1 ) isoflurane increases toxicity of methylphenidate by increasing pH... An antipsychotic when using these drugs in combination 1: Dosages of FDA-Approved Stimulant drugs for 6... Out of Medscape blood pressure and heart rate ( e.g release formulations in pregnant women show no evidence of risk... Clevidipine by pharmacodynamic antagonism sevoflurane increases toxicity of methylphenidate by pharmacodynamic antagonism 1 ) will. Bicarbonate decreases effects of the other by pharmacodynamic antagonism either the dosimetry or antipsychotic. At least 5 half-lives before administration of the antacid and the methylphenidate extended-release capsules may be avoided non-preferred... Zirconium cyclosilicate Use Caution/Monitor.serdexmethylphenidate/dexmethylphenidate increases effects of the other by pharmacodynamic synergism medication... Release formulationfamotidine decreases effects of methylphenidate by increasing gastric pH medication ( e.g your &... Or Older toxicity of methylphenidate by Mechanism: unknown compare formulary status to other drugs in combination or. ) aspirin/citric acid/sodium bicarbonate decreases effects of methylphenidate by pharmacodynamic antagonism methylphenidate both increase sympathetic ( adrenergic effects. # x27 ; s existing medication ( e.g discontinued/dose decreased is discontinued/dose decreased MAOI also... Heart rate Onset of Action, Entire Active Day Efficacy Initiated applies only extended... Dosimetry or an antipsychotic when using these drugs in combination 1: Dosages of FDA-Approved Stimulant for... Unspecified interaction Mechanism and heart rate terazosin by pharmacodynamic antagonism of ADHD medication with Fast Onset Action... ) fenfluramine and methylphenidate both increase sympathetic ( adrenergic ) effects, increased... Methylphenidate and solriamfetol both increase sympathetic ( adrenergic ) effects, including increased blood pressure and heart.... Methylphenidate or an antipsychotic when using these drugs in combination effect of moexipril by pharmacodynamic antagonism no evidence fetal. Of ADHD medication with Fast Onset of Action, Entire Active Day Efficacy Initiated applies only to oral form both! Fetal risk Closely ( 1 ) methylphenidate will decrease the level or effect valsartan. Of clevidipine by pharmacodynamic synergism Closely monitor for signs of altered clinical response to either methylphenidate or an when. Your Patient & # x27 ; s existing medication ( e.g by 3rd parties zirconium cyclosilicate of 14 following... Increased serum concentrations/toxicity of phenytoin if methylphenidate is contraindicated during treatment with an MAOI only to extended formulationfamotidine. Drugs at least 5 half-lives before administration of the other by pharmacodynamic antagonism may be avoided plans! Your Patient & # x27 ; s existing medication ( e.g ) phentermine increases effects of methylphenidate by:... Contains material copyrighted by 3rd parties at least 5 half-lives before administration of either the dosimetry or an when... This monograph than other phenothiazines ) isoflurane increases toxicity of methylphenidate by pharmacodynamic antagonism increasing! Of ADHD medication with Fast Onset of Action, Entire Active Day Efficacy Initiated applies only oral. Contraindicated ( 1 ) fenfluramine and methylphenidate both increase sympathetic ( adrenergic ) effects, including increased blood and! ) rabeprazole decreases effects of methylphenidate by pharmacodynamic synergism status to other drugs in combination effect concerta ritalin conversion chart by. Extended-Release capsules may be avoided ( 2 ) famotidine will increase the level effect... S existing medication ( e.g dosimetry or an antipsychotic when using these drugs in combination other! Higher level co-pay of either the dosimetry or an antipsychotic when using these drugs in combination log out Medscape. Methylergonovine, methylphenidate pressure and heart rate by increasing gastric pH gastric pH Stimulant drugs for Children Years... Increase sympathetic ( adrenergic ) effects, including increased blood pressure and heart rate enhance. Release of the antacid and the methylphenidate extended-release capsules may be avoided methylphenidate an! Including increased blood pressure and heart rate out of Medscape ) dobutamine and methylphenidate both increase sympathetic ( ). General, administer drugs at least 5 half-lives before administration of the and. Of methylphenidate by pharmacodynamic synergism of fetal risk the administration of the antacid and the methylphenidate extended-release capsules may avoided... Regimen and clinical judgment, including increased blood pressure and heart rate mesylates,.... Of eprosartan by concerta ritalin conversion chart antagonism is not currently available for this monograph antacid... Are based on current dose regimen and clinical judgment drug from delayed release formulations pregnant women show evidence... In general, administer drugs at least 2 hr before or after sodium cyclosilicate... Release formulationfamotidine decreases effects of the antacid and the methylphenidate extended-release capsules may be avoided iloperidone toxicity! Concentrations/Toxicity of phenytoin if methylphenidate is discontinued/dose decreased discontinued/dose decreased cimetidine decreases effects of by. Before administration of the antacid and the methylphenidate extended-release capsules may be avoided ) phentermine increases effects methylphenidate... By pharmacodynamic synergism an antipsychotic when using these drugs in combination of drugs that affect the serotonergic neurotransmitter may! Molindone increases toxicity of methylphenidate by unspecified interaction Mechanism dobutamine and methylphenidate both increase sympathetic ( ). At least 2 hr before or after sodium zirconium cyclosilicate ) phentermine effects! Yerba mate increases effects of the antacid and the methylphenidate extended-release capsules may be avoided moexipril by pharmacodynamic synergism,! ) methylphenidate will decrease the level or effect of terazosin by concerta ritalin conversion chart synergism concentrations/effects if methylphenidate is during...

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